Abstract
Background: The neutrophil-lymphocyte ratio (NLR) acts as an indicator of subclinical inflammation. Inflammatory marker NLR significantly increases in prediabetic and diabetic patients. Periodontal therapy can contribute to diabetes control in diabetic patients with periodontitis. Aims and Objectives: The aim of this study is to evaluate Neutrophil Lymphocyte ratio in type 2 diabetes mellitus patients before and after Non-surgical periodontal therapy. Materials and Methods: A cross-sectional prospective study was carried with a sample size of 90 patients having Type 2 Diabetes Mellitus. Venous blood samples were collected from each patient at baseline and 1 month after delivering NSPT. NLR was assessed and comparatively evaluated before and after treatment. Results: There are significant differences in NLR values of diabetic patients at baseline and at one month post non-surgical periodontal therapy (p = 0.004). Mean NLR values are higher in diabetic patients at baseline (2.07 ± 0.55) compared to mean NLR of 1.37 ±0.46 one month after delivering NSPT. Conclusion: Non-surgical periodontal therapy significantly reduces the NLR in diabetic patients. NSPT may augment diabetes control in patients with Type 2 Diabetes Mellitus.
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