Abstract

During the experiment, 180 mongrel male rats at the age of 4 months (corresponding to approximately 27-28 human years) were irradiated with γ-quanta 60Co with an energy of 1.2 MeV single and fractionated (in uniform portions for 5 days) in total doses of 50 cGy at a dose rate of 50 cGy/h. Neuromorphological changes of the sensorimotor cortex of the cerebral hemispheres in the III and V layers (respectively small and large pyramidal neurons) were studied.

Highlights

  • During the experiment, 180 mongrel male rats at the age of 4 months were irradiated with γ-quanta 60Co with an energy of 1.2 MeV single and fractionated in total doses of 50 cGy at a dose rate of 50 cGy/h

  • The number of destructive neurons depended on all modes of irradiation, but their dynamics was more strongly influenced by fractionated effects

  • The protein content in neurons depended on single irradiation, which is two times more affected the dynamics of the index compared to fractionated

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Summary

Introduction

180 mongrel male rats at the age of 4 months (corresponding to approximately 27-28 human years) were irradiated with γ-quanta 60Co with an energy of 1.2 MeV single and fractionated (in uniform portions for 5 days) in total doses of 50 cGy at a dose rate of 50 cGy/h. Ushakov IB*, Fedorov VP, Komarevtsev VN and Dyachkov AA

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