Comparative evaluation of hemodynamic and capnographic changes in low pressure versus normal pressure pneumoperitoneum in laparoscopic cholecystectomy

Abstract

Background: In laparoscopic cholecystectomy (LC), the extent of hemodynamic changes associated with creation of pneumoperitoneum depends on the intra-abdominal pressure attained, volume of CO2 absorbed, and patient’s intravascular volume. In our study, we attempted to compare the hemodynamic and capnographic changes in the low pressure (<8mm Hg) and standard pressure (12-14mm Hg) LC.Methods: In this randomized case control study, Group A included patients undergoing Low pressure LC (<8mm Hg). In group B, Standard pressure LC (12-14mmHg) was performed. Both groups were evaluated for the hemodynamic and capnographic changes and other parameters.Results: Difference in mean heart rate of Group A and Group B was found to be statistically significant at 10 min after induction. After 30 minutes of surgery, systolic blood pressure of Group B was found to be higher than that of Group A (p <0.05). Differences in diastolic blood pressure among patients of Group A and Group B were found to be statistically significant only at 30 min and 40 min after induction. Except at 30 min after induction, differences in EtCO2 levels of patients of Group A and Group B were found to be statistically significant.Conclusions: It appears that low pressure pneumoperitoneum appears to be having fewer effects on blood pressure- both systolic and diastolic, as compared to standard pressure pneumoperitoneum in patients undergoing LC. It also appears to be causing fewer derangements in ETCO2. This may help in smooth recovery and less post-operative problems.