Comparative evaluation of crystalloid coloading and colloid coloading for prevention of spinal anaesthesia induced hypotension in patients undergoing elective caesarian section

Abstract

The most prevalent consequence after a caesarean surgery is post-spinal hypotension. To avoid this, crystalloid or colloid cohydration might be utilized. We aimed to see how crystalloid and colloid coloading affected hemodynamics and neonatal outcome in patients undergoing elective caesarean section, following spinal anesthesia. A total of 100 pregnant women were enrolled in this study, which were split into two groups of 50 each. Group A was given 10ml/kg Ringer Lactate (RL) And Group B patients received 10ml/kg 6% hetastarch coloading. Patients were monitored for Mean SBP, DBP, MAP, HR, SPO2, mean APGAR score of newborn at 1 and 5 minutes post delivery, the prevalence of nausea and vomiting as well as Vasopressor requirement. The incidence of hypotension was higher in the crystalloid group, as was the need for Vasopressor, compared to the colloid group. The crystalloid group had a higher rate of nausea and vomitingIn the colloid group, hemodynamics such as SBP, DBP, MAP, and HR were more stable. However, as demonstrated by the APGAR score of 1 in both groups, there was no difference in neonatal outcome.Colloid coloading is more effective method of preventing post spinal hypotension in patients undergoing caesarean section however combined use of Vasopressor and fluids seems to be more effective way of managing post spinal hypotension.