COMPARATIVE EVALUATION OF ANAESTHETIC EFFICACY OF ARTICANE 4%, BUPIVACAINE 0.5% AND LIDOCAINE 2% FOR INFRAORBITAL NERVE BLOCK: A RANDOMIZED CLINICAL TRIAL

Abstract

Aim:The aim of this clinical trial was compare of anaesthetic efficacy of articane 4%, bupivacaine 0.5% and lidocaine 2% for infraorbital nerve block. Materials And Methods: 75 patients were randomly assigned in to 3 groups where they were injected with eitherarticane 4%, bupivacaine 0.5% and lidocaine 2% and their anaesthetic efficacy was checked . Normality testing was done using the Shapiro-Wilk test. Data for EPT failed normality and hence, non-parametric tests were used for analysis. The EPT scores for pain threshold were compared between the three groups using Kruskal-Wallis test (non-parametric ANOVA) at pre-dosing, post-dosing, 1 hour, 2 hours and 3 hours. Post-hoc Mann-Whitney U test was used for pair-wise comparisons at all time periods. Results:As per the results obtained from the present study, the post-dosing results with electronic pulp tester was highest with Articaine followed by lignocaine and was least with bupivacaine. This showed that the Articaine had early onset amongst all three and bupivacaine showed late onset. Conclusion:This study shows that statistically significant difference was observed between lidocaine, Articaine and bupivacaine.Articaine has a faster onset and provides clinically effective anaesthesia in root canal treatment and other restorative procedures.