Abstract
Background: Trigonella foenum-graecum is one of the commonly used herbs in food. Moringa oleifera is a source of food, accommodation and conventional medicine for many peoples in the developing countriesThe seeds of both the plants were explored for antidiabetic potential.
 Methods: The current work was designed to probe the in vitro anti diabetic potential of the aqueous seed elicit of trigonella foenum- graceus and Moringa oleifera using the enzymes alpha amylase and alpha glucosidase.Both the extracts were screened for their phytochemicals and antioxidant potential was also analysed.The data were examine statistically by a one-way analysis of variance (ANOVA) followed by Duncan’s multiple range test was used to see the statistical significance in conjunction with groups. The results with the p<0.05 level were considered to be statistically significant.
 Result: Due to its chemical ingredient and active compounds like amino acids, alkaloids, flavonoids, it proceeds as a good antioxidant. Trigonella foenum-graecum seed extract exhibited comparatively higher antidiabetic potential with an IC50 of 300µg/ml than the Moringa oleifera extract. Results of the work designate that both extracts of the plant possessed by forbidding alpha amylase, alpha glucosidase show maximum inhibition. Hence concluded that, Trigonella foenum graecum leaves might be considered as herbal remedies for diabetes.
 Conclusion: In vitro antioxidant and antidiabetic potential of seed elicit of Trigonella foenum-graecum and Moringa oleifera were analyzed and compared. This study shows that Trigonella foenum-graecum has higher antidiabetic potential than the Moringa oleifera extract.
Highlights
Trigonella foenum-graecum is an herb extensively cultivated in India and some parts of China.In India,seeds are used as condiments [1]
This study shows that Trigonella foenum-graecum has higher antidiabetic potential than the Moringa oleifera extract
Trigonella foenumgraecum is a self pollinating crop and it is a vernacular plant used to make maple syrup and the steroid saponin are used widely in industries.Trigonella foenum-graecum is rich in calcium,iron,beta carotene,vitamins,lipids [4] and the seeds are rich in carbohydrates and proteins.It is used as a folk treatment for non insulin dependent diabetes [5]
Summary
Trigonella foenum-graecum is an herb extensively cultivated in India and some parts of China.In India,seeds are used as condiments [1]. It is an annual plant, which belongs to the family leguminosae 1 [2]. Methods: The current work was designed to probe the in vitro anti diabetic potential of the aqueous seed elicit of trigonella foenum- graceus and Moringa oleifera using the enzymes alpha amylase and alpha glucosidase.Both the extracts were screened for their phytochemicals and antioxidant potential was analysed.The data were examine statistically by a one-way analysis of variance (ANOVA) followed by Duncan’s multiple range test was used to see the statistical significance in conjunction with groups.
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