Abstract
Background: Rapid, accurate, point-of-care detection of influenza virus infection is desirable for the outpatient management of children. Several collection methods including nasopharyngeal wash (NPW), nasopharyngeal swab (NPS) and nasal swab (NS) are available for testing by commercially available rapid influenza diagnostic tests. Unfortunately, the collection of nasopharyngeal specimens by NPW is uncomfortable and time-consuming. Swabs of the nose and pharynx are better tolerated by patients and easier to collect. To date, however, no studies have compared the yield from swabs (NPS and NS) to that from NPW for diagnosing influenza in children. Study Objective: To compare the diagnostic yield of a rapid antigen detection test for influenza in samples obtained by three different specimen collection methods.
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