Abstract

Shilajeet, a polycrest ayurvedic drug hitherto unknown for its hypolipidemic effect has been shown to lower serum cholesterol, liver cholesterol, serum triglycerides and serum phosphlipids of wistar rats fed on a cholesterol (1%) supplemented diet, by 39, 55, 47 and 25 per cent respectively, when 0.2 per cent of it was incorporated in the diet. In comparison, gum guggal (2.0 per cent in the diet) lowered the serum cholesterol, liver cholesterol, serum triglycerides and serum phospholipids by 36, 60, 49 and 8 per cent respectively. The increase in HDL-cholesterol by shilajeet was much higher (53%) compared to that by gum guggal (29%).

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