Comparative Efficacy of Advanced Surgical Hemostats in Canine Hepatotomy

Syed Wasim Abbas,Muhammad Naveedali,Muhammad Arif Khan,Hamid Akbar,Ghulam Abbas,Muhammad Asif

doi:10.13189/azb.2018.060204

Abstract

In the present study Hemostatic effects of Surgicel Snow and Surgicel Fibrillar in 12 cases in dogs were observed. The dogs were divided into three groups via group A, B and C with four dogs in each group. All three groups were anesthetized by the combination of xylazine (1.1mg/kg) and ketamine (5.5mg/kg) administered intravenous. Group A received Surgical Gauze, Surgicel Snow was employed in Group B and Surgicel Fibrillar was used in Group C. Hemostasis time, Liver function test (LFT), Complete blood count (CBC), Temperature, Pulse rate and Respiratory rate (TPR), Ultrasonography were evaluated. Hemostasis time was significantly less in animals who had received a Surgicel Snow compared to Surgicel Fibrillar and Surgical Gauze. LFT values were significantly different among all three groups. CBC values also differ among all groups. In TPR there were no significant differences in all groups. All groups showed no changes during Ultrasonography of liver. Surgicel Snow is better hemostat than Surgicel Fibrillar with minimum blood loss and least effects on liver function.

Highlights

Hepatic surgeries are very common in canines
Total 36 samples of blood were collected before surgery, after surgery, at 7 day and at 14 day to perform Alanine Amino-transferase (ALT), Aspartate Amino-transferase (AST), and Alkaline Phosphatase (ALP) tests
Ultrasonography was performed at 7 days and 14 days among all 12 dogs (n=4) treated with Surgical Gauze, Surgicel Snow and Surgicel Fibrillar

Summary

Introduction

Hepatic injuries cause serious health issues which may result in death of animals. Despite all recent developments in surgical techniques during liver surgery, blood loss is still one of the main causes for postoperative morbidity and mortality [1]. Hemostasis is the key to successful surgery which benefits the patient, the surgical team and the health care facility. Bleeding occur in traffic accidents remains one among the most causes of traffic accident deaths. Hemorrhage can occur after trauma which can leads to death It is the major cause of operating room mortality among patients who undergo liver surgery [5].After the establishment of safe airway and ensuring the proper oxygenation and ventilation, the best priority in the handling of the traumapatient is to control hemorrhage. The development of more effective hemostatic agents is critical in order to keep surgical costs down and provide the best safety for patients [7]

Materials and Methods

Results

Surgical Methods

Discussion