Abstract

The goal of comparative effectiveness research is to improve health care while dealing with the seemingly ever-rising cost. An understanding of comparative effectiveness research as a core topic is important for neuroradiologists. It can be used in a variety of ways. Its goal is to look at alternative methods of interacting with a clinical condition, ideally, while improving delivery of care. While the Patient-Centered Outcome Research initiative is the most mature US-based foray into comparative effectiveness research, it has been used more robustly in decision-making in other countries for quite some time. The National Institute for Health and Clinical Excellence of the United Kingdom is a noteworthy example of comparative effectiveness research in action.

Highlights

  • The Institute of Medicine provided the current definition of comparative effectiveness research (CER) as “the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent, diagnose, treat, and monitor a clinical condition or to improve the delivery of care.”[5]. The purpose of CER is to help all role groups associated with the health care enterprise make informed decisions useful in the management of an individual patient

  • The Patient-Centered Outcomes Research Institute The PCORI set about identifying research priorities and developing an agenda that will inform the various participants

  • On March 5, 2012, the Board of Governors approved the following definition of patient-centered outcomes research: “Patient-centered outcomes research helps people and their caregivers communicate and make informed health care decisions, allowing their voices to be heard in assessing the value of health care options.”[23]

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Summary

Introduction

Graduates of the Edinburgh Medical School developed a concept of “arithmetical medicine.”[1,2] Dr Lind’s historic controlled study of 6 different treatments for scurvy was, in reality, the first true “evidence” of comparative effectiveness research (CER).[3] In the early 20th century, Ernest Codman started looking at “outcomes management” in patient care.[4] The Institute of Medicine provided the current definition of CER as “the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent, diagnose, treat, and monitor a clinical condition or to improve the delivery of care.”[5] The purpose of CER is to help all role groups associated with the health care enterprise make informed decisions useful in the management of an individual patient.

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