Abstract

# {#article-title-2} To the Editor: Drs. French and England1 appropriately point out the importance of comparative effectiveness research. In the accompanying editorial, Drs. Dorsey and Meltzer2 also emphasize that research in this area is important. Comparative medication effectiveness is part of the consideration of medical cost-effectiveness in general, which would also include the value of laboratory studies. For example, what is the value of repeated brain MRI studies in patients with stable multiple sclerosis? Probably minimal. Since comparative medication effectiveness research is important, I thought it was ironic that in the same issue of Neurology ®, Dr. French et al.3 have a research publication where this was not practiced. French et al. investigated brivaracetam (BRV) treatment in seizure patients. Three concentrations of adjunctive BRV …

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