Abstract
CS Murray. M Thomas. K Richardson. DB Price. SW Turner. J Allergy Clin Immunol Pract. 2017;5(4):1082–1090.e7 Current guidelines offer a number of different choices for step-up treatment of uncontrolled asthma in children on low-dose inhaled corticosteroids (ICSs). In this study, the authors compared the relative effectiveness of step-up treatment to fixed-dose combination (FDC) ICSs and long-acting β2-agonists as opposed to an increased dose of inhaled corticosteroids (i-ICSs) or adding a leukotriene receptor antagonist (LTRA). This matched cohort study included children with uncontrolled persistent asthma aged 5 to 12 years from 2 UK primary-care databases who were receiving …
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