Abstract
Clinical evidence suggests that T2DM and its complications can be prevented through regular intake of functional foods. This cost-effective way of managing T2DM in developing world might prove very beneficial. A randomized controlled trial was done to compare effects of Fenugreek and Cinnamon on treatment of newly diagnosed cases of T2 DM. Subjects were selected from Pakistan Institute of Medical Sciences Hospital, Islamabad. Study was carried out in three phases: Phase I, baseline; Phase II, after 90 days and Pahse III at end of washout period. Subjects, from both genders, were within the age range of 40-65 years. There were 26 subjects in each group. Serum levels of FPG, HbA1c, fasting insulin levels, lipid profile were measured at baseline and at the end of 2nd and 3rd phases. BMI, WC and WHR were also studied in all phases of the study. SPSS (version 22) was used for analysis. Cinnamon seemed to have more effect on both anthropometric (BMI & WC) and biochemical (FPG, HbA1c, serum Insulin, serum cholesterol, HDL & LDL) parameters, as compared to Fenugreek, which had effect on WC, FPG, HbA1c, serum cholesterol and TG only. Although, the magnitude of these effects was similar in both groups.
Highlights
All foods which contain biologically active ingredients are considered to be functional foods because of their health benefits associated with prevention of certain NCDs like DM
Clinical evidence suggests that T2DM and its complications can be prevented through regular intake of functional foods (Alkhatib et al, 2017; Venkatakrishnan et al, 2019)
The study was conducted at Medical Outpatient Department (OPD) of Pakistan Institute of Medical Sciences (PIMS), which is a tertiary care hospital, located in Islamabad, capital of Pakistan
Summary
All foods which contain biologically active ingredients are considered to be functional foods because of their health benefits associated with prevention of certain NCDs like DM. Many studies focused on the herbal remedies which played role in the treatment of Diabetes (Acevedo et al, 2017; Choudhury et al, 2017; Shahzad et al, 2020). There were 451 million people with T2DM all over the world by year 2017, and this number was expected to rise to 693 million by year 2045 (Ogurtsova et al, 2017). About 5 million deaths all over the world were attributable to Diabetes in year 2017. Clinical evidence suggests that T2DM and its complications can be prevented through regular intake of functional foods (Alkhatib et al, 2017; Venkatakrishnan et al, 2019)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
