Abstract

Differences between alveolar macrophages (AM) and peritoneal macrophages (PM) have been reported by several investigators. Myrvik et al. [1], Dannenberg et al. [2], Cohn and Wiener [3], and Leake et al. [4], foundthat rabbit AM contained higher levels of hydrolases than oil-induced PM, and that AM exhibited a higher rate of endogenous oxygen consumption than oil-induced PM [4]. Oren et al. [5] studied the phagocytic process in guinea pig AM and casein-induced PM and reported that AM depend to a considerable degree upon oxidative phosphorylation as a source of energy for phagocytosis. In contrast, PM apparently depend only on glycolysis as the source of energy for that function.

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