Abstract

A crystallographic comparison comprised of some geometrical and structural features of a steroids series (pregnane derivatives) is made in the present paper. Some selected bond distances and bond angles of interest are discussed in detail. Conformations of individual ring systems in a series of 46 pregnane derivatives have been calculated and discussed. Correlation of ring conformations especially the rarer ones, vis-a-vis the multiple bonds and ring junctions has been discussed. Graphical presentations of ring conformations are made for all the five- and six-membered rings to show the relative frequency of their occurrence. 17β-side chain conformation is discussed in some pregn-20-one structures. X–H···A intra- and intermolecular interactions in the identified derivatives have been discussed with the standard distance and angle cut-off criteria. Distance-angle scatter plots for both kinds of interactions are presented for a better understanding of the packing interactions which exist in pregnane molecules.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.