Abstract
The chemical and analgesic comparison of essential oils of Cymbopogon nardus (L) Rendle of Benin and Congo was investigated. The chemical analysis wa carried out by using GS/MS for identification of components of the two essential oils while acetic acid-induced writhings, hot plate and tail flick test models were used for analgesic activity. The results showed that the two essential oils exhibited comparable activity on acetic acid-induced writhings, however, the essential oil of Benin induced more significant effect on hot plate model while the Congolese specie showed more effect in the tail flick test. These observations could be explained by some qualitative and/or quantitative differences observed between the constituents of the two essential oils studied.
Highlights
Cymbopogon nardus (C. nardus) (L) Rendle, a Poaceae is a medicinal plant widely used as culinary (Konwar and Gohain, 1999) and for perfemury (Furukawa, 1918)
Leaves of C. nardus collected from Loufoulakari, Brazzaville in the department of Pool (Congo) and from Cotonou (Benin) with voucher number Kami 1501 were botanically identified in the Centre d’Etudes sur les Ressources Végétales (CERVE) of Brazzaville (Congo)
C. nardus leaves of Benin and Congo were subjected to hydrodistillation to obtain essential oils
Summary
Cymbopogon nardus (C. nardus) (L) Rendle, a Poaceae is a medicinal plant widely used as culinary (Konwar and Gohain, 1999) and for perfemury (Furukawa, 1918). The Chinese use the leaves for rheumatism and other uses in the treatment of fever, intestinal parasites, digestive and menstrual problems. C. nardus produced a yellow essential oil which present some pharmacological properties as antifungal (Awuah, 1999), repellent against mosquito (Ansari and Razdan, 1995; Ranaweera and Dayananda, 1996). Literature is poor on the analgesic effect and African comparative study of chemical compounds of essential oil of this plant. The aim of the present study is to compare the chemical and analgesic properties of essential oils of C. nardus of Benin with those of Congo
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