Comparative assessment of renal complications in children during the COVID-19 pandemic

Ismoilova Ziyoda Aktamovna Ismoilova Ziyoda Aktamovna,Muhammad Arsalan Ali Sajid Muhammad Arsalan Ali Sajid,Kilicheva Tuxtagul Abdullayevna Kilicheva Tuxtagul Abdullayevna

doi:10.30574/wjarr.2022.13.2.0032

Ismoilova Ziyoda Aktamovna Ismoilova Ziyoda Aktamovna, Muhammad Arsalan Ali Sajid Muhammad Arsalan Ali Sajid + Show 1 more

Open Access

https://doi.org/10.30574/wjarr.2022.13.2.0032

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Abstract

Although medically children are not at risk, but in the ongoing COVID 19 pandemic has serious implications for children. New evidence do not clearly define renal manifestations. Among the reasons for the lack of efficacy of the ongoing treatment of patients with renal complications, an incomplete understanding of its pathogenesis in children who have had a coronavirus infection plays a special role. Biochemical blood tests revealed the elevated blood and urine MC levels which in 1/5 of the patients with high parameters. Moderate proteinuria and transient macrohaematuria were observed in children in the COVID-19 group with renal complications. Children with moderate to severe ChKD with COVID-19 or with recurrent nephrotic syndrome are at risk of severe complications, including severe AKF or ChKF. This data indicates that the children with COVID-19 infection should be closely monitored for the development and progression of RF and special measures should be taken to prevent it.

Highlights

Medically children are not at risk, the ongoing COVID 19 pandemic has serious implications for children [1]
Moderate proteinuria and transient macrohaematuria were observed in children in the COVID-19 group with renal complications
Children with moderate to severe ChKD with COVID-19 or with recurrent nephrotic syndrome are at risk of severe complications, including severe AKF or ChKF

Summary

Introduction

Medically children are not at risk, the ongoing COVID 19 pandemic has serious implications for children [1]. Among the reasons for the lack of efficacy of the ongoing treatment of patients with renal complications, an incomplete understanding of its pathogenesis in children who have had a coronavirus infection plays a special role [2, 3]. It is not known whether the virus directly affects the kidneys or whether renal complications are a side-effect of the infection. The number of victims of this dangerous infection is rising, and the overall prognosis is not encouraging It is under these difficult conditions that doctors and scientists have to investigate how the virus affects the body [7,8,9]. Diagnosis of renal dysfunction, and evaluation of clinical and laboratory characteristics in children with renal complications formed against the background of COVID-19

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