Abstract

Comparative anatomical, histological, and histochemical study of liver in human and domestic rabbit

Highlights

  • IntroductionThe human liver is the largest organ in the body with an average of 1500 gram in weight

  • Anatomical and histological structure of the liver varies in different species

  • The liver of domestic rabbit consists of multiple lobules, each composed of irregular plates of hepatocytes with intervening sinusoids which drain into central vein, the cells are polyhedral with acidophilic cytoplasm and prominent nuclei [8,9]

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Summary

Introduction

The human liver is the largest organ in the body with an average of 1500 gram in weight. It is situated in the right hypochondrium under the right dome of diaphragm [1]. The liver of domestic rabbit is soft lobulated organ lies in the epigastric region below the diaphragm It extends between the costal arches from the 7th right rib to the 9th left rib and touches the left and right abdominal walls [6,7]. The liver of domestic rabbit consists of multiple lobules, each composed of irregular plates of hepatocytes with intervening sinusoids which drain into central vein, the cells are polyhedral with acidophilic cytoplasm and prominent nuclei [8,9]. The lack of studies that compare the anatomical and histological characteristics of human liver and rabbit liver encourage us to do this study aiming to observe, compare and differentiate the anatomy, histology and histochemistry of human liver with that domestic rabbit to assess the quality of liver of domestic rabbit to be used in the experimental studies

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