Abstract

Various schemes to represent functioning of the mechanism of presynaptic inhibition were investigated on an electronic model. During direct activation of deprocessing neurons of the substantia gelationsa by afferent fibers the transition process was considerably prolonged. An increase in following frequency led to a decrease in amplitude of stabilized spikes followed by a gradual rise. In another scheme with polysynaptic activation of depolarizing neurons through collaterals of intermediate nerve cells responses were nearest to natural. Comparison of transitional and steady-state regimes obtained and investigated on the model and in experiments on cats showed that the scheme with activation of gelatinosa neurons by a negative feedback circuit is the most acceptable.

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