Abstract

During recent four decades, the world has faced two horrific, deadly pandemics. In the background of the ongoing pandemic HIV/AIDS, the people were affected with the newly emerging Corona virus SARS-CoV-2, that rapidly turned into pandemic dimensions. There are data that, in various aspects, HIV infection was similar to SARS-CoV-2. The purpose of this review was to search for similarities and differences between both pandemics in view to use the experience of the past and knowledge we have acquired in order to better overcome current and future pandemics. Material/Methods: The iterature used is based on databases PubMed, Embase and random search on the Internet with the keywords COVID-19 and HIV, as well the Boolean operator "AND" to achieve a search of "COVID-19 and HIV". Review Results: In the present review summary, we provide data for similarities and differences regarding virological, immunologic, clinical and pharmacological aspects of HIV and SARS-CoV-2 infections and associated with them pandemics. Conclusion: SARS-CoV-2 was here and will remain here. COVID-19 is not the last pandemic, and people should be prepared for new encounters with agents of high virulence and pandemic potential.

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