COMPARATIVE ANALYSIS OF OSSEOINTEGRATION WITH OR WITHOUT PRF (PLATELET RICH FIBRIN) IN ORAL IMPLANTOLOGY- A RANDOMIZED PROSPECTIVE CLINICAL STUDY

Abstract

Introduction Dental rehabilitation of partially or totally edentulous patients with dental implants has become a popular treatment modality with reliable long-term results. These days’ new methods are being used to improve the quality of osseointegration. Platelet Rich Fibrin (PRF) is a second generation platelet concentrate which is a new biotechnology, it has been suggested to be of great use in implant dentistry as it can enhance the quality of osseointegration. Various studies show that it improves healing of both hard as well as soft tissues. Aim To compare the quality of osseointegration using platelet rich fibrin over conventional implant placement. Materials & Methods 40 dental implants were placed in total for this study. 20 implants each were placed with PRF (Goup A) and without PRF (Group B) in the osteotomy site. After three months CBCT was done to evaluate and compare the quality of osseointegration between the 2 groups measured in gray value using the Galileos Implant Software- Sirona. Result Mean values obtained were ≈1928 in group A (with PRF) and ≈1734.6 in group B (without PRF). Independent Samples T-Test showed a significant p-value of 0.013 ( p-value>0.05). Conclusion Results from our study show that PRF can play a promising role in the quality of osseointegration when used as a biomaterial in oral implantology. Our study provides a basis for future research with larger sample size and longer follow-ups to elucidate this outcome further.