Abstract

Aim. It was conducted a comparative determination of matrix metalloproteinase- 9 in 116 patients with ischemic cerebral infarction, hemorrhagic stroke, ischemic stroke with hemorrhagic transformation in patients with circulatory encephalopathy.Methods and results. The study determined that the concentration of MMP-9 in patients with hemorrhagic stroke and ischemic stroke with hemorrhagic transformation is higher than in patients with ischemic stroke.Conclusion. It was determined that in patients with ischemic stroke , in which MMP- 9 is below 50 ng / ml , hemorrhagic transformation were not observed regardless of the severity of the condition and volume of the lesion.

Highlights

  • С целью определения содержания протеолитического фермента ММП-9 обследовали 116 пациентов с мозговым ишемическим инфарктом, геморрагическим инсультом, ишемическим инсультом с геморрагической трансформацией, а также с дисциркуляторной энцефалопатией

  • The study determined that the concentration of MMP-9 in patients with hemorrhagic stroke and ischemic stroke with hemorrhagic transformation is higher than in patients with ischemic stroke

  • It was determined that in patients with ischemic stroke, in which MMP- 9 is below 50 ng / ml, hemorrhagic transformation were not observed regardless of the severity of the condition and volume of the lesion

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Summary

Conclusion

It was determined that in patients with ischemic stroke , in which MMP- 9 is below 50 ng / ml , hemorrhagic transformation were not observed regardless of the severity of the condition and volume of the lesion. 1) показали, что на первые сутки заболевания концентрация ММП-9 у больных ИИ, ГИ и ИИГТ достоверно повышалась на 59,3% (р

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