Comparative analysis of blood hematological and biochemical indices in children with different vitamin provision

Abstract

Aim. To study the peculiar features of hemogram indices and biochemical indices of blood in children with different vitamin provision.
 Materials and methods. Vitamin A, C, D, E, B6 and B12 content in blood was determined in 188 children (aged 5–6 years) of pre-school educational institutions (PEI), who attended PEI for not less than 3 years and had a standard C-vitaminised diet.
 Results. The study of a season provision with vitamins A, C, D, E, B6 and B12 showed that 75–85 % of children have a whole-year deficit of vitamins, characterized as polyhypovitaminosis in 40 %. Comparative analysis of blood hematological and biochemical indices in children with different vitamin provision was carried out.
 Conclusions. Among children with insufficient vitamin provision there was noted more stressed state of hemopoietic erythrocytic blast and decreased proliferative activity of lymphomonocytic blast against the background of higher activity of allergic-type cell responses; lower level of protein, carbohydrate, mineral and energetic metabolism is observed in children with insufficient vitamin provision.