Abstract
<p><em>This study was</em><em> a</em><em> </em><em>true e</em><em>xperimental study </em><em>using the </em><em>randomized controlled group method with a </em><em>pre</em><em>-</em><em>post test</em><em> design</em><em>. </em><em>The </em><em>Sprague-Dawley rats </em><em>were </em><em>divided into 4 groups (5</em><em> rats/</em><em>group</em><em>):</em><em> K (+) Captopril 0</em><em>,</em><em>45 mg/200 g BW, goldenberry juice 1</em><em>,</em><em>8 ml/200 g BW</em><em> (P1)</em><em>, cucumber juice 1</em><em>,</em><em>8 ml/200 g BW</em><em> (P2)</em><em>, and 1</em><em>,</em><em>8 ml/200 g BW (</em><em>P3, </em><em>combination juice 50%:50%). Systolic blood pressure measured by blood pressure analyzer with the tail-cuff method. The result of systolic blood pressure analyzed by Paired t-Test to determine the mean difference of systolic blood pressure before and after 8% NaCl induction. One Way ANOVA test followed by Post Hoc Duncan to determine the mean difference of systolic blood pressure between groups.</em><em> Goldenberry, cucumber, and combination juice have a significant effect of reducing systolic blood pressure in hypertension with p = 0</em><em>,</em><em>000 (&lt;0</em><em>,</em><em>05). Goldenberry juice was </em><em>the </em><em>most effectively on reducing systolic blood pressure in hypertension with 42.21%.</em><em></em></p>
Highlights
This study was a true experimental study using the randomized controlled group method with a pre-post test design
The Sprague-Dawley rats were divided into 4 groups (5 rats/group): K (+) Captopril 0,45 mg/200 g BW, goldenberry juice 1,8 ml/200 g BW (P1), cucumber juice 1,8 ml/200 g BW (P2), and 1,8 ml/200 g BW (P3, combination juice 50%:50%)
Systolic blood pressure measured by blood pressure analyzer with the tail-cuff method
Summary
Data tekanan darah awal diperoleh pada hari ke-8 setelah masa aklimatisasi untuk mengetahui tekanan darah awal. Tekanan darah sistolik tikus diukur kembali pada hari ke-18 untuk mengetahui tekanan darah sebelum masa perlakuan jus. Hasil analisis statistik menunjukkan bahwa NaCl 8% yang diberikan 3 ml/hari secara oral dapat meningkatkan tekanan darah sistolik secara bermakna selama 10 hari masa perlakuan dengan p=0,000 (
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