Comparación entre la eficacia de la vareniclina y la terapia de reemplazo nicotínico para la cesación tabáquica

Abstract

After a description of the patient, a smoker that had relapsed after bupropion therapy and wishes to make a new quit attempt,the options of nicotine patches and varenicline appear. After posing the question and performing the literature search, theonly relevant paper is selected. Some aspects of smoking are reviewed, and the only article detected is summarized. This trial showed that varenicline was more efficacious than nicotine replacement therapy at the end of treatment (primaryoutcome) though there were no differences at one year (secondary outcome). It is concluded that more studies with a better design and longer follow up are needed to be able to detect long term difference in cessation rates that compare both active strategies