Abstract

ObjectiveTo assess the repeatability and comparability of the central corneal thickness measurements obtained from a novel Scheimpflug camera with a Placido-disc topographer (Sirius®) and ultrasound pachymetry. Material and methodsIn a sample of thirty unoperated eyes of healthy subjects, the central corneal thickness was analyzed by a single examiner using the Sirius® and the ultrasound pachymeter. Repeatability of three sets of measurements from each device were evaluated using the coefficient of variation, standard deviation, and intraclass correlation coefficient. T-test with Bonferroni adjustment and Bland and Altman plots were used to assess agreement between devices. ResultsFor the Sirius® the coefficient of variation was 0.291%, and for the ultrasound pachymeter was 0.238%. The standard deviation was 0.123μm and 0.101μm for Sirius® and US respectively and the intraclass correlation coefficient was higher than 0.95 in all measurements. Ultrasound pachymetry systematically yielded higher values and statistically significant (mean 543.867 vs 558.267μm Sirius® and ultrasound pachymeter respectively), but the difference was not clinically significant. ConclusionIn the assessment of normal corneas, central corneal thickness measured with both devices showed high repeatability and good agreement. Even though central corneal thickness measurements obtained by Sirius® were systematically lower than those obtained by ultrasound pachymeter, they do not have clinical significance.

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