Abstract
Acromegaly is a disease characterized by a slowly progressive somatic disfigurement caused by the overproduction of growth hormone (GH) and insulin-like growth factor 1 (IGF-1), mainly associated with a pituitary adenoma. The most evident manifestation at the facial level is a mandibular prognathism due to excess growth of the jaw. The purpose of this work was to perform a craniofacial morphological comparison through cephalometric analysis and cephalometric superimposition between a patient diagnosed with acromegaly and his twin brother who does not have the disease. Our results showed that in the acromegalic patient there is a significant increase in the size of the sella turcica, an anterior displacement of the maxilla and mandible, being the mandibular displacement more marked. The morphological change experienced by the mandible in acromegaly is mainly attributed to the growth of the mandibular ramus due to an increase in the condylar unit.
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