Comorbidity of impulse control disorders and major depression in Parkinson’s disease with multiple stressogenic factors: An intensive multimodal complex therapy.

Abstract

Parkinson’s disease (PD) is a neurodegenerative disorder that is characterized by symptoms that impact both motor and non-motor domains [1]. The disease causes a range of movement symptoms such as balance and gait control disturbance as well as tremor. PD with comorbid major depression and impulse control disorder (ICDs) associated with various stressors not only negatively influence the overall course of disease and treatment but also lead to disability. Whereas there is a well-established treatment guideline for PD, there is no common consent protocol for an effective depression and ICDs therapy in PD Patients.