Comorbidity in inflammatory diseases of joints and spine (clinical aspects)

Abstract

The article presents an analysis of the current view of comorbidity problem in rheumatology from the perspective of inflammatory disorders of the joints and spine combination with the most common diseases of the internal organs and endocrine system. The data gained from recent sources regarding the frequency and structure of concomitant disorders in patients with rheumatoid arthritis (RA) and spondylarthritis (ankylosing spondylitis [AS] and psoriatic arthritis [PsA]) are presented. It has been shown that the most common comorbidity in patients with RA, AS, PsA are diseases of the gastrointestinal tract and cardiovascular diseases. The authors present the results of their own research on the study of comorbidity in RA, AS and PsA, which are consistent with modern literature data. It is noted that there are specific disease-associated factors, as well as the negative effect of anti-inflammatory drugs in the development and manifestation of comorbid pathology.