Abstract

Multiple Sclerosis (MS) is a chronic autoimmune disabling disease that is caused by autoimmune attack of myelin in the central nervous system [1]. Disease is not treatable and the progression depends on disease course and presence of comorbidity [2]. Among plenty of comorbid conditions that are present during MS duration, connection between primary headache and MS is well known but still poorly understood. Primary comorbid headache might be a cause of decreased quality of life of patients with MS. Mostly it depends on the type of primary headache and type of MS course (3).

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