Abstract
Object To investigate the effective therapeutic to control nephric colic without anesthetics by comparing the different drugs. Methods 512 patients with moderate or severe nephric colic (the severity of pain was scored by verbal report) were randomized into three groups, including (1) group pethidine +654-2, (2) group lornoxicam + 654-2,and (3) group rotundine +654-2. The effects on alleviation of pain were evaluated among three groups within 40 minutes after drug administration.Results The excellence rate iss 86% and effective rate is 90% in group pethidine + 654-2. The excellence rate are 70% and 65%, respectively,in group lornoxicam + 654-2 and group rotundine +654-2, which are both lower than that in group pethidine +654-2 (both P＜ 0.05), however, the effective rates were 92% and 89%, respectively, which are not significantly different from that in group pethidin + 654-2 (both P＞ 0.05). Comclusion Lornoxicam and rotundine can be widely used to replace pethidine to alleviate nephric colic. Key words: Nephric Colic; Community; Alleviation of Pain; Medicinal Treatment
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