Abstract
BackgroundPrevious studies suggest that health intervention designed to increase cervical cancer screening has been effective to reduce cervical cancer incidence and mortality. The aim of this study is to determine the effect of a home-based health education intervention for increasing cervical cancer screening uptake delivered by trained female community health volunteers (FCHVs), a category of community health worker in Nepal.MethodsA community-based, open-label, two-armed, cluster-randomized trial [seven clusters (geographical wards) randomized for the intervention, and seven for the control arm]. The participants are recruited from a population-based survey with a sample size of 884. Based on population proportion size, 277 women will be recruited for the intervention group and 413 women recruited for the control group. A 12-month community-based health education intervention will be administered mobilizing the FCHVs, based on the Health Belief Model. The primary outcome measure of the study will be the difference in percentage of cervical cancer screening uptake between the two study arms. The primary outcomes will be modeled by using mixed-effect logistic regression analysis.DiscussionCOBIN-C is the first study investigating the effect of a community-based health education intervention by FCHVs on increasing cervical cancer screening uptake among women in Nepal. The purpose of this study is to develop and implement a home-based, culturally sensitive program to increase cervical cancer screening coverage at the community level.Trial registrationClinicalTrials.gov NCT03808064. Registered on January 14, 2019.
Highlights
Previous studies suggest that health intervention designed to increase cervical cancer screening has been effective to reduce cervical cancer incidence and mortality
What is non-communicable diseases (NCDs) and its situation in Nepal? What are the different types of NCDs? What are the risk factors for NCDs? How can we prevent NCDs?
The COBIN-C study is the first investigation of a community-based intervention to increase cervical cancer screening uptake in Nepal
Summary
Previous studies suggest that health intervention designed to increase cervical cancer screening has been effective to reduce cervical cancer incidence and mortality. Cervical cancer is a common cancer among women in most low- and middle-income countries (LMICs) in Asia, Africa, and Latin America [1]. It is the major cause of cancer deaths among women in Nepal with an estimated 2942 new cases and 1928 deaths in 2018 [1]. There are very limited tools and skilled health professionals available for cervical cancer screening in many LMICs, including Nepal. There is a need for appropriate, cost-effective, and sustainable interventions to increase VIA screening uptake at the primary health care level across Nepal
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