Abstract

Background : Community-based cardiac rehabilitation interventions have been known as an important aspect of secondary prevention. However, no data are available regarding the benefit of this program in Indonesian coronary artery disease (CAD) patients treated with optimal medication. Objectives : To assess the benefit of community-based cardiac rehabilitation on patient adherence to the drugs, quality of life (QoL) and MACE, in stable CAD. Methods : An observational prospective cohort study recruited the Malang community of cardiovascular care (MC3) members as an intervention group and Aisyah Islamic hospital patients in Malang, Indonesia, as a control, for a year follow up. Member of MC3 has regular aerobic exercise, education regarding the disease, the importance of the drugs, and its side effect in addition to standard education given in outpatient clinic setting as the control group members. A validated MMS-8, QOL (SF-36), and SAQ questionnaire were used to assess adherence to the drugs, QoL, and MACE of participants. Results: A total of 73 interventions and 73 control patients were enrolled for the study. Our findings showed that intervention patients were 2.04-fold associated with having a better physical function and 3.85-fold better compliance than control patients. The hospitalization rate also significantly lower in members of the intervention group (MC3). However, no significant difference observed among the two groups. Moreover, in the subgroup analysis, it shows that the intervention group who had participated for 2 years had the highest value of MMS-8 compared to the other groups with p < 0.005. Conclusion: Our study reveals that community based cardiac rehabilitation intervention have better adherence to medication and quality of life than patients control, and also could reduce rehospitalization in stable CAD patients.

Highlights

  • Cardiovascular disease is a major cause of heart failure and premature deaths worldwide

  • No data are available regarding the benefit of this program in Indonesian coronary artery disease (CAD) patients treated with optimal medication

  • In the subgroup analysis, it shows that the intervention group who had participated for 2 years had the highest value of MMS-8 compared to the other groups with p < 0.005

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Summary

Introduction

Cardiovascular disease is a major cause of heart failure and premature deaths worldwide. Revascularization either with percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) is more effective in treating angina, reducing of anti-angina drugs need, improving exercise capacity, and quality of life, compared to medical treatment strategies alone.[4] After revascularization procedures, the coronary artery disease (CAD) patients recommended to perform in hospital base followed by community based cardiac rehabilitation. Community-based cardiac rehabilitation interventions have been developed to improve the patient's adherence to the guideline recommendations, with more or less impact on the achievement of outcome improvement.[6] Adherence to the recommended-treatment has a favorable effect on morbidity and mortality in the follow-up period.[6] no research has been done in Indonesia measuring the role of community-based cardiac rehabilitation on the adherence of patients with stable coronary artery disease. Our results were supposed to provide the benefit of community-based cardiac rehabilitation in reducing morbidity and mortality rates as well

Study design
Participants & eligibility criteria
Ethical approval
Data Collection
Measure
Statistical Analysis
Patients selections
Baseline characteristics
Main findings
Correlation between adherence and MACE
Reduction of rehospitalization in intervention group
Discussion
Declarations
Pusat Komunikasi Publik Sekretariat Jenderal Kementerian Kesehatan
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