Abstract

There are three sure things in life: death, taxes and antimicrobial resistance appearing on the heels of the introduction and widespread use of an antimicrobial agent. Staphylococcus aureus has always been a poster child for the emergence of antimicrobial resistance (1). Penicillin‐resistant strains of S aureus surfaced immediately following the introduction of penicillin in the late 1940s; within a few years, most hospital strains were penicillin resistant. There was also the rapid emergence of methicillin‐resistant S aureus (MRSA) following the introduction of methicillin in the 1960s. While the replacement of nosocomial methicillin‐susceptible S aureus by MRSA has proceeded at different rates in different regions, the overall global progression has been relentless. MRSA became common in Canadian health care facilities later than in the United States; however, since the early 1990s, nosocomial MRSA in Canada has steadily and irrevocably increased (2).

Highlights

  • There are three sure things in life: death, taxes and antimicrobial resistance appearing on the heels of the introduction and widespread use of an antimicrobial agent

  • The current chapter in this story is the progressive dissemination of community-acquired methicillin-resistant S aureus (MRSA) (CAMRSA), mirroring the experience with penicillin-resistant S aureus 50 years ago (1)

  • CAMRSA has been common in some Canadian communities for almost 20 years (3)

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Summary

Introduction

There are three sure things in life: death, taxes and antimicrobial resistance appearing on the heels of the introduction and widespread use of an antimicrobial agent. The current chapter in this story is the progressive dissemination of community-acquired MRSA (CAMRSA), mirroring the experience with penicillin-resistant S aureus 50 years ago (1). CAMRSA has been common in some Canadian communities for almost 20 years (3). Even in communities with long-standing experiences with CAMRSA, more severe S aureus infections may be recognized.

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