Abstract
In the treatment of infertility, many methods for assisted oocyte activation have been proposed, yet each has drawbacks that could limit the efficiency of or introduce uncertainty to the activation. This study adopts a physical approach, using nanosecond pulsed electric fields (nsPEFs) to trigger repetitive calcium oscillations in mouse oocytes, which boosts the activation rate and improves embryo development. The underlying activation mechanism is unveiled via simulations based on a kinetic calcium-channel model. This effective, controllable technique may provide a better solution to male infertility.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
