Abstract
BackgroundCommon variable immunodificiency syndrome predominantly affects adults. It is characterized by low production of all the major classes of immunoglobulins. We report a case of common variable immunodeficiency syndrome with right aortic arch. An association of right-sided arch and common variable immunodificiency syndrome has not been previously reported.Case presentationA 41-year-old female patient presented with a history of recurrent pneumonia, sinusitis, otitis media, diarrhoea, cystitis since childhood. Biochemical and immunocytochemical analysis revealed common variable immunodeficiency syndrome and radiological evaluation confirmed right aortic arch and aberrant left subclavian artery.ConclusionCommon variable immunodeficiency syndrome syndrome is a clinical entity that should be kept in mind in patients with recurrent infections of different sites.
Highlights
BackgroundCommon variable immunodeficiency (CVID) is the most prevalent primary immunodeficiency, and predominantly affects adults
Common variable immunodificiency syndrome predominantly affects adults
Common variable immunodeficiency syndrome syndrome is a clinical entity that should be kept in mind in patients with recurrent infections of different sites
Summary
Common variable immunodeficiency (CVID) is the most prevalent primary immunodeficiency, and predominantly affects adults. A 41-year-old woman admitted to infectious diseases clinics with productive cough, fatigue and postnasal drip for three days She reported repetitive attacks of sinusitis, otitis media, diarrhoea (giardiasis and amebiasis were detected many times), cystitis and pneumonia since childhood. She had a history of symptomatic therapy (non-specific antibiotics). The right displacement of aortic arcus was noticed on plain chest radiography (Figure 1) and high-resolution computerized tomography (CT) scanning of the thorax revealed right aortic arch, aberrant left subclavian artery (Figure 2), and bronchiectasis on both lower lobes of lungs (Figure 3). Our patient had a history of recurrent lower respiratory tract infection attacks since her childhood and was diagnosed bronchiectasis on lower lobes of both lungs with HRCT. Routine histological examination of lymphoid tissues usually reveals germinal centre hyperplasia, which may be difficult to distinguish from nodular lymphoma [6]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
