Common Interferences Removal from Dense Multichannel EEG Using Independent Component Decomposition.

Abstract

To improve the spatial resolution, dense multichannel electroencephalogram with more than 32 leads has gained more and more applications. However, strong common interference will not only conceal the weak components generated from the specific isolated neural source, but also lead to severe spurious correlation between different brain regions, which results in great distortion on brain connectivity or brain network analysis. Starting from the fast independent component analysis algorithm, we first derive the mixing matrix of independent source components based on the baseline signals prior to tasks. Then, we identify the common interferences as those components whose mixing vectors span the minimum angles with respect to the unitary vector. By assuming that both the common interferences and their corresponding mixing vectors stay consistent during the entire experiment, we apply the demixing and mixing matrix to the task signals and remove the inferred common interferences. Subsequently, we validate the method using simulation. Finally, the index of global coherence is calculated for validation. It turns out that the proposed method can successfully remove the common interferences so that the prominent coherence of mu rhythms in motor imagery tasks is unmasked. The proposed method can gain wide applications because it reveals the true correlation between the local sources in spite of the low signal-to-noise ratio.