Comments on: Methylene blue? Therapeutic altternative in the management of septic shock refractory to norepinephrine

Alberto Pasqualucci ,Filomena Puntillo ,Giustino Varrassi

doi:10.22514/sv.2020.16.0115

Abstract

Signa Vitae is an international peer-reviewed open access journal, which is currently indexed in SCIE, scopus, etc. It covers many aspects of adult, pediatric and neonatal intensive care, anesthesia and emergency medicine

Highlights

Dear Editor, We read with pleasure the paper “Methylene blue? Therapeutic alternative in the management of septic shock refractory to norepinephrine”, published by Aragon-Benedi C et al [1] in the last issue of Signa Vitae
This is characterized by a decrease of systemic vascular resistances (SVR) and abnormal distribution of blood flow, with normal or increased cardiac output (CO) [3]
Whatever the cause might be, hemodynamic shock is characterized by a decrease in tissue perfusion associated with cellular and metabolic abnormalities

Summary

Introduction

Dear Editor, We read with pleasure the paper “Methylene blue? Therapeutic alternative in the management of septic shock refractory to norepinephrine”, published by Aragon-Benedi C et al [1] in the last issue of Signa Vitae. Therapeutic alternative in the management of septic shock refractory to norepinephrine”, published by Aragon-Benedi C et al [1] in the last issue of Signa Vitae. Shock, defined as an acute syndrome of circulatory failure leading to inadequate oxygen delivery to the cells, is most of the time “distributive” (62% of the cases) [2]. This is characterized by a decrease of systemic vascular resistances (SVR) and abnormal distribution of blood flow, with normal or increased cardiac output (CO) [3].

Results

Conclusion