Abstract
Autism spectrum disorder (ASD) was proposed in the Diagnostic and Statistical Manual of Mental Disorders version 5 (DSM-5), released May 2013. The new diagnosis encompasses previous diagnoses of autistic disorder, Asperger’s syndrome, childhood disintegrative disorder, and pervasive developmental disorder not otherwise specified (PDD-NOS). So ASD is a group of developmental disabilities that can cause significant social, communication and behavioral challenges. To estimate a prevalence is 0.1%–1%. The importance of lifelong influence and social burden has attracted extensive attention and focus of research. Searching for the cause of ASD is the hotspot of medical study in China and all of the world recently.
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