Commentary to ‘Does bladder augmentation negatively affect renal transplant outcome in PUV patients?’

Abstract

The authors present data on their experience with bladder augmentation in children undergoing transplantation for posterior urethral valves. Most of their augmented patients (10/12) were with a ureter. They found a higher incidence of urinary tract infections(UTIs) in the augmented group, but graft function and survival were similar. The presence of vesicoureteral reflux was the major risk factor in both groups. Even though this is one of the larger series of patients with posterior urethral valves undergoing transplantation, the numbers are still too small to determine if bladder augmentation is a confounding factor and if vesicoureteral reflux is not the main factor responsible for the increased incidence of UTIs. Does bladder augmentation negatively affect renal transplant outcome in posterior urethral valve patients?Journal of Pediatric UrologyVol. 10Issue 5PreviewAlthough renal transplant (RT) is a safe and effective treatment for end-stage renal disease, the outcome of RT has been mixed for posterior urethral valve (PUV) patients. In addition, some PUV patients need an augmentation cystoplasty (AC), which may negatively affect their RT outcome. The aim of this study is to compare RT outcome between PUV children with and without AC. Full-Text PDF