Commentary: The oral microbiome in young women at different stages of periodontitis: Prevotella dominant in stage III periodontitis.

Abstract

young women with stage-III periodontitis by 16S rRNA-sequencing (Zhao et al., 2022). We greatly appreciate 16 this work and believe that the conclusion has potential value. However, we need to point out that the study 17 protocol has some limitations, which may affect the accuracy of the conclusions.First, only 26 young women with periodontitis were included in this study. We think that the small 19 sample size will affect the ability to analyze alpha diversity analysis for the oral microbiome. Second, 20 dysbiosis of oral microbial ecology is both a major causative factor for oral diseases such as periodontitis and 21 is also closely associated with systemic diseases (Issrani et al., 2022;Xu et al., 2022 The authors declare that the research was conducted in the absence of any commercial or financial 60 relationships that could be construed as a potential conflict of interest.