Abstract

Commentary: Phage Therapy of Staphylococcal Chronic Osteomyelitis in Experimental Animal Model.

Highlights

  • Specialty section: This article was submitted to Antimicrobials, Resistance and Chemotherapy, a section of the journal Frontiers in Microbiology

  • Phage therapy in many cases has been used as a means of treating chronic bacterial infections which may be tolerant to antibiotic treatment rather than necessarily genetically resistant

  • What is going on is that phage therapy has been used to treat bacterial infections against which antibiotics, often following months or years of treatment, have not been successful (e.g., Rhoads et al, 2009; Wright et al, 2009; Miedzybrodzki et al, 2012)

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Summary

Sublethal systemic infection

∼108 CFU/ml reduced to ∼104 CFU/ml in feces

Sinusitis model
Findings
Chronic osteomyelitis
Full Text
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