Abstract

A recent review [H.Tedeschi, Old and New Data, New Issues: the Mitochondrial Δ ψ, Biochim. Biophys. Acta, Bioenerg. (2005)] has questioned the validity of experiments performed more than 30 years ago that provided the first quantitative estimates of the protonmotive force generated by mitochondria. This commentary explains that the review author's confusion stems from ignoring the data in these papers on the trans-membrane pH gradient.

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