Abstract
Yong et al. methodically evaluated the role of the long noncoding RNA (lncRNA) DLEU2/miR-529-3p/HOXB2 axis in Wilm's tumor pathogenesis [1]. Through a set of nicely designed experimental studies, the investigators examined the expression of the novel lncRNA DLEU2 in primary Wilm's tumor tissue, Wilm's tumor cell lines, and a xenograft model, and evaluated its regulation by the microRNA miR-539-3p and involvement in expression of the oncogene HOXB2. While previously found to have relevance in other malignancies, this is the first comprehensive evaluation of the expression of these nucleotides with Wilm's tumor progression.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
