Abstract
This special issue amply fulfils its aim of moving the study of gene × environment (GE) interplay forward constructively and creatively, exploiting contributions from diverse disciplines. Rather than discussing the many interesting findings and methods in this special issue, I will comment on two cross-cutting issues – one about genes and the other about the environment – that came to mind as I read these articles.
Highlights
This special issue amply fulfils its aim of moving the study of gene 9 environment (GE) interplay forward constructively and creatively, exploiting contributions from diverse disciplines
What we have learned from the whirlwind of genome-wide association (GWA) studies during the past few years is that the biggest effect sizes for associations between genes and traits – both for common disorders and quantitative dimensions – are much smaller than anyone expected
A polygenic score constructed from 32 single nucleotide polymorphisms (SNPs) shown to be associated with body mass index (BMI) has been used in several studies
Summary
MRC Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, King’s College London, London,UK. This special issue amply fulfils its aim of moving the study of gene 9 environment (GE) interplay forward constructively and creatively, exploiting contributions from diverse disciplines. Rather than discussing the many interesting findings and methods in this special issue, I will comment on two cross-cutting issues – one about genes and the other about the environment – that came to mind as I read these articles
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