Abstract

Commentary: Lessons from the Analysis of Non-human Primates for Understanding Human Aging and Neurodegenerative Diseases.

Highlights

  • A commentary on Lessons from the analysis of nonhuman primates for understanding human aging and neurodegenerative diseases by Verdier J, Acquatella I, Lautier C, Devau G, Trouche S, Lasbleiz C, et al Front Neurosci (2015) 9:64. doi:10.3389/fnins.2015.00064

  • We agree with Verdier et al (2015) that the use of animals may be scientifically viable in some areas of research, but we feel that the animal model is not sufficiently evidence-based to be considered as a valid predictive modality for the study of human disease

  • The MPTP primate model of Parkinson’s disease (PD) proposed by Burns et al (1983) followed the observation of a case of parkinsonism occurring after the self-administration by a 23-year-old man of an illicit synthetic drug [1-methyl-4-phenyl-4-propionoxy-piperidine (MPPP)]

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Summary

Introduction

A commentary on Lessons from the analysis of nonhuman primates for understanding human aging and neurodegenerative diseases by Verdier J, Acquatella I, Lautier C, Devau G, Trouche S, Lasbleiz C, et al Front Neurosci (2015) 9:64. doi:10.3389/fnins.2015.00064. 1 Antidote Europe, Perpignan, France, 2 Bordeaux Polytechnic Institute, Bordeaux, France Keywords: non-human primate, Parkinson’s disease, animal model, prediction, neuromodulation

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