Abstract
Commentary: Introduction to the Frontiers Research Topic: Optimization of Exercise Countermeasures for Human Space Flight-Lessons From Terrestrial Physiology and Operational Considerations.
Highlights
This Commentary addresses the paper “Introduction to the Frontiers Research Topic: Optimization of Exercise Countermeasures for Human Space Flight–Lessons from Terrestrial Physiology and Operational Considerations” recently published by Scott et al (2019)
The paper authored by Scott et al has at least one shortcoming that comes from ignoring the key point that physical exercise has the potential to increase free radical production and lead to oxidative stress (Cooper et al, 2002)
It has been shown that low-dose rate radiation exposure (e.g., ∼100 mSv for half a year on the International Space Station, dose rate ∼0.6 mSv/d) can lead to oxidative stress “Results from astronauts participating in 4- to 6-month missions reveal increased carotid intima-media thickness (Arbeille et al, 2016) and vascular stiffness (Hughson et al, 2016) that are suggested to be related to increased oxidative stress, inflammation, and insulin resistance” (Garrett-Bakelman et al, 2019)
Summary
This Commentary addresses the paper “Introduction to the Frontiers Research Topic: Optimization of Exercise Countermeasures for Human Space Flight–Lessons from Terrestrial Physiology and Operational Considerations” recently published by Scott et al (2019). A Commentary on Introduction to the Frontiers Research Topic: Optimization of Exercise Countermeasures for Human Space Flight–Lessons From Terrestrial Physiology and Operational Considerations by Scott, J.
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