Abstract
Commentary: Differential Risk of Dementia Between Patients With Atrial Flutter and Atrial Fibrillation: A National Cohort Study.
Highlights
Division of Cardiology, Department of Medical Sciences, “Città della Salute e della Scienza di Torino” Hospital, University of Turin, Turin, Italy
On two propensity-matched cohorts from Taiwan’s National Health Insurance Research Database and another dataset, atrial fibrillation (AF) relates to an increased risk of dementia compared to atrial flutter (AFL), independently from oral anticoagulation
If on one hand this increased risk of dementia can be partly explained by an increased propension of AF patients to suffer an ischemic stroke, both in non-anticoagulated (HR 1.76, 95% CI 1.56–1.98) and anticoagulated subjects (HR 2.54, 95% CI 1.56–4.12), other mechanisms might certainly be involved
Summary
A Commentary on Differential Risk of Dementia Between Patients With Atrial Flutter and Atrial Fibrillation: A National Cohort Study by Wang, H.-T., Chen, Y.-L., Lin, Y.-S., Chen, H.-C., Chong, S.-Z., Hsueh, S., Chung, C.-M., and Chen, M.-C., (2021). The pathophysiological background and the clinical presentation of the two conditions are different, related to the ventricular response, completely irregular (“irregularly irregular”) during AF, while generally regular (or, at least, a “regular/modular irregularity”) during AFL.
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