Abstract

Commentary: Differential Humoral and Cellular Immunity Induced by Vaccination using Plasmid DNA and Protein Recombinant Expressing the NS3 Protein of Dengue Virus type 3

Highlights

  • Dengue is a viral infection transmitted by mosquitoes (Aedes aegypti y A. albopictus) causing flu-like symptoms, sometimes the disease evolves into a deadly condition known as severe dengue (before dengue hemorrhagic fever)

  • As it is known, dengue is a viral infection transmitted by mosquitoes (Aedes aegypti y A. albopictus) causing flu-like symptoms, sometimes the disease evolves into a deadly condition known as severe dengue

  • The controversy and suspension of the vaccination campaign was due to the low efficacy of the Dengvaxia® vaccine, it was because the vaccine increased the risk of severe dengue and hospitalization of people without prior exposure to the virus, this has caused skepticism about the safety of this vaccine

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Summary

Introduction

Dengue is a viral infection transmitted by mosquitoes (Aedes aegypti y A. albopictus) causing flu-like symptoms, sometimes the disease evolves into a deadly condition known as severe dengue (before dengue hemorrhagic fever). The immunity generated against other serotypes in a second infection represents a great risk, since this induced immunity increases in the patient the risk of suffering from severe dengue[2].

Results
Conclusion

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