Abstract

A recent Nature article provided preliminary evidence that infants age 2–6 months old, who were later diagnosed with Autism Spectrum Disorder (ASD), fixated more on the mouth than eyes and more at objects than people when viewing videos of typical childhood social scenes (1). While the sample was small, a reliable pattern of decline in eye fixation accurately predicted their level and classification of symptoms at age three suggesting that – for the first time – an infant could be assessed within the first 6 months of life for their potential of developing ASD (see Table ​Table11 for studies that used eye-tracking with infants 12 months and younger). These eye-tracking devices, which are currently in clinical trials, could provide access to an affordable and objective tool with the potential for extremely early intervention. Detecting ASD risk during the first 6 months of life presents unprecedented opportunities to intervene, providing children opportunities to build critical skills before autistic characteristics fully emerge. Because the eye-tracking device allows for a non-invasive, portable assessment, the device could also enable pediatricians to provide comparable screening services globally. With such promise, a near future where infants are placed into an eye-tracking device at routine pediatric visits is compelling, if not guaranteed.

Highlights

  • Specialty section: This article was submitted to Child Health and Human Development, a section of the journal Frontiers in Public Health

  • A commentary on Attention to eyes is present but in decline in 2–6-month-old infants later diagnosed with autism by Jones W, Klin A

  • A recent Nature article provided preliminary evidence that infants age 2–6 months old, who were later diagnosed with Autism Spectrum Disorder (ASD), fixated more on the mouth than eyes and more at objects than people when viewing videos of typical childhood social scenes [1]

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Summary

Location of recruitment

Infants who attended more to mouths in complex scenes, London, UK regardless of risk for ASD, developed better expressive language skills. Infants later diagnosed with ASD have difficulty attending less New Haven, CT, USA to faces and less to areas of speaker’s faces that would provide verbal cues. Infants later diagnosed with ASD attend more to mouths

Infants later diagnosed with ASD attend less attention to
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